Adapting Treatment Delivery to Improve Retention in Evidence-Based PTSD Treatment

Completed · Not applicable

Conditions studied: Stress Disorders, Post-Traumatic

In brief

Posttraumatic stress disorder (PTSD) is prevalent among Veterans and effective evidence-based psychotherapies (EBPs) for PTSD have been implemented within the Veterans Health Administration (VHA). However, retention in PTSD EBPs is poor. Premature dropout is associated with worse clinical outcomes and greater healthcare utilization. Delivery of PTSD EBPs in a massed format, typically three or more days per week delivered within a month, have shown promise for increasing retention. The present study is a pilot feasibility and acceptability study comparing massed PTSD treatment to treatment as usual (e.g., typically weekly treatment).

Key facts

Study ID

NCT06335589

Run by

VA Office of Research and Development

People needed

30

Starts

2024-06-24

Expected to finish

2025-09-15

Last updated by the study team

2026-01-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Veterans aged 18 years or older;
• meets criteria for current PTSD;
• willingness to be randomized to either condition (e.g., EBP-Massed or EBP-TAU);
• decision to receive CPT or PE in a treatment planning session with a Durham Trauma Recovery Program clinic provider;
• ability to provide informed consent

You may not qualify if…

• High acute suicide risk;
• active manic symptoms that would likely interfere with treatment;
• active psychotic symptoms that would likely interfere with treatment;
• currently in a concurrent trauma-focused evidence-based treatment for PTSD

Where it is running

• Durham VA Medical Center, Durham, NC — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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