Autoantibodies Against-nephrin in Idiopathic Nephrotic Syndrome

Recruiting now

Conditions studied: Nephrotic Syndrome

In brief

This retrospective study is aimed at evaluating the levels of circulating anti-nephrin autoantibodies in patients with INS, including those with MCD/FSGS and in patients who have experienced relapse of FSGS post-transplant, compared to those of a control group of patients with nephrotic syndrome due to primary membranous nephropathy (MN).

Key facts

Study ID

NCT06334692

Run by

Mario Negri Institute for Pharmacological Research

People needed

100

Starts

2024-03-19

Expected to finish

2028-03-01

Last updated by the study team

2025-09-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult (>18 years) males and females
• Patients with biopsy-proven idiopathic MCD or FSGS (cases)
• Patients with biopsy-proven idiopathic membranous nephropathy (controls)
• Patients who provided consent to store their samples in the certified CRB biobank

You may not qualify if…

• Reasonable possibility of a secondary cause of NS (for cases) or MN (for controls) at time of blood collections
• Active viral or bacterial infections at time of blood collections

Where it is running

• Clinical Research Center for Rare Disease Aldo e Cele Daccò — Ranica, BG, Italy (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.