Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients

Recruiting now · Not applicable

Conditions studied: Moyamoya Disease, Moyamoya

In brief

Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression. Main tasks are: * Analysis of CO2-triggered BOLD fMRI for analysis of cerebral hemodynamics in comparison to H2 15O PET/CT * Analysis of longitudinal changes of contrast enhancement in vessel-wall imaging and correlation of disease activity with biosampling * Definition of a standardized recommendation for pre- and postoperative imaging of Moyamoya patients

Key facts

Study ID

NCT06330818

Run by

University Hospital Tuebingen

People needed

50

Starts

2024-07-01

Expected to finish

2027-11-30

Last updated by the study team

2024-09-26

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients with suspicion of Moyamoya Disease
• Patients able to understand the study and to give their informed consent

You may not qualify if…

• Cerebral vascular disease caused by atherosclerosis
• Vasculitis
• Contraindications to MRI
• Contraindications to PET/CT
• Pregnancy
• Inability to give informed consent
• Renal insufficiency

Where it is running

• University of Tuebingen, Neurosurgery — Tübingen, Baden-Wurttemberg, Germany (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.