COgnitive Dynamics in Early Childhood

Recruiting now

Conditions studied: Cognitive Change

In brief

The goal of this accelerated longitudinal observational cohort study is to advance our understanding of cognitive variability in children aged 7 to 10 at first measurement. The CODEC study aims to integrate experience sampling methods, longitudinal designs, deep phenotyping cohorts, and state-of-the-art statistical methodologies to investigate three core questions: 1. How does cognitive variability differ between individuals? 2. What are the neural, psychological, and environmental mechanisms that underlie cognitive variability? 3. What are the long-term consequences and outcomes associated with differences in cognitive variability?

Key facts

Study ID

NCT06330090

Run by

Radboud University Medical Center

People needed

600

Starts

2024-11-18

Expected to finish

2027-12-01

Last updated by the study team

2025-04-11

Who can join

Age: 7 and older, up to 13. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• In order to be eligible to participate in the behavioural arm of this study, a subject must meet all of the following criteria:
• Between the ages of 7 and 10 years at the moment of the first assessment. In order to be eligible to participate in the imaging arm of this study, a subject must meet all of the following criteria:
• Between the ages of 8 and 10 years at the moment of the first assessment.

You may not qualify if…

• A potential subject will be excluded from participation in the study if the participant indicates not understanding the instructions of the behavioural tasks due to a language barrier. In the imaging arm of the study, a potential subject who meets any of the following criteria will further be excluded from participation in the imaging arm of the study:
• History of neurological or psychiatric illness.
• History of using psychotropic medications.
• Contraindications for MRI.
• Metal parts that cannot be removed, are present in or on upper body, e.g. plates, screws, aneurysm clips, metal splinters, piercings or medical plasters. (exception: dental fillings, crowns, a metal wire behind the teeth, tattoos and contraceptive coils).
• Body containing metal fragments, in particular in the eye, e.g., caused by injuries when working with metal.
• History of brain surgery.
• Active implant(s) (e.g. pacemaker, neurostimulator, insulin pump, ossicle prosthesis)
• Using a medical plaster that cannot or may not be taken off (e.g. nicotine plaster)

Where it is running

• Radboudumc Department of Cognitive Neuroscience — Nijmegen, Netherlands (enrolling)

Full record on ClinicalTrials.gov

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