Itch Sensation Induced by Simultaneous Application of Pruritogens (Spatial Summation)
Recruiting now · Not applicable
Conditions studied: Histamine, Cowhage
In brief
In This experiment, the investigators would like to design a new itch model based on the spatial summation of pruritic stimuli. The hypothesis behind this study (spatial summation) is that two simultaneous applications of pruritogens will result in higher itch sensation compared with a single application of pruritogen.
Key facts
- Study ID
- NCT06328530
- Run by
- Aalborg University
- People needed
- 24
- Starts
- 2024-04-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2024-05-06
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy men and women
- 18-60 years
- Speak and understand English
You may not qualify if…
- Pregnancy or lactation
- Drug addiction defined as any use of cannabis, opioids, or other addictive drugs
- Previous or current history of neurological (e.g. neuropathy), immunological (e.g. asthma, immune deficiencies, arthritis) musculoskeletal (e.g. muscular pain in the upper extremities,), cardiac disorder, or mental illnesses that may affect the results
- Lack of ability to cooperate
- Current use of medications that may affect the trial such as antihistamines, antipsychotics, and pain killers, as well as systemic or topical steroids
- Skin diseases (e.g. atopic dermatitis, pruritus nodularis, eczema, psoriasis)
- Moles, scars, or tattoos in the area to be treated or tested.
- Consumption of alcohol or painkillers 24 hours before the study days and between these
- Acute or chronic pain
- Participation in other trials within one week of study entry (four weeks in the case of pharmaceutical trials)
Where it is running
- Aalborg University — Aalborg, Denmark (enrolling)
Full record on ClinicalTrials.gov
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