Modulating Reward Learning Using Transcranial Magnetic Stimulation

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Behavior

In brief

Our specific aim is to examine the effects of TMS on reward processing during goal-directed behavior. In these experiments the investigators will utilize a scalp-recorded brain oscillation called frontal midline theta that is believed to index the sensitivity of the cingulate cortex to reward feedback. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in decision making tasks, and if so, whether it would affect the encoding of rewards and subsequent choices during task performance.

Key facts

Study ID

NCT06323057

Run by

Rutgers, The State University of New Jersey

People needed

28

Starts

2024-02-14

Expected to finish

2026-04-30

Last updated by the study team

2025-11-18

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Be between the ages of 18 and 55 years old.
• Be in stable mental and physical health.
• If female, test non-pregnant.
• Be willing to provide informed consent.
• Be able to comply with protocol requirements and likely to complete all study procedures.

You may not qualify if…

• Contraindication to rTMS (history of neurological disorder or seizure, increased intracranial pressure, brain surgery, or head trauma with loss of consciousness for > 15 minutes, implanted electronic device, metal in the head, or pregnancy).
• History of autoimmune, endocrine, viral, or vascular disorder affecting the brain.
• Life time history of mental disorders such as: Bipolar Affective disorder (BPAD), Schizophrenia, Post-traumatic Stress disorder (PTSD) or Dementia or Major Depression.
• uninterruptable central nervous system medication

Where it is running

• Rutgers University - Newark — Newark, New Jersey, United States (enrolling)

Full record on ClinicalTrials.gov

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