High Flow Nasal Cannula Weaning in Acute Bronchiolitis

Recruiting now · Not applicable

Conditions studied: Acute Bronchiolitis

In brief

The goal of this clinical study is to compared two different strategies to end high flow nasal cannula treatment in acute bronchiolitis. This study compared the immediate ending of high flow treatment to weaning strategy, in which the flow rate is gradually decreased. The aim is to assess if the immediate ending shortens the hospitalization time and whether it is a safe strategy.

Key facts

Study ID

NCT06321133

Run by

Kuopio University Hospital

People needed

50

Starts

2024-02-13

Expected to finish

2028-12-31

Last updated by the study team

2025-09-03

Who can join

Age: any, up to 1. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinically diagnosed acute bronchiolitis
• High flow nasal cannula treatment has lasted for at least 12 hours
• Measured saturation 95 or more with room air
• High flow rate is maximum 2l/kg/min
• The treating doctors considers the infant suitable to be without high flow

You may not qualify if…

• Major congenital anomaly of lungs, hearts or diaphragm
• Bacterial pneumonia
• Parents do not give consent

Where it is running

• Siun Sote — Joensuu, Finland (enrolling)
• Central Finland Hospital District — Jyväskylä, Finland (enrolling)
• Kuopio University Hospital — Kuopio, Finland (enrolling)
• Mikkeli Central Hospital — Mikkeli, Finland (enrolling)

Full record on ClinicalTrials.gov

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