Examination of Psychological and Physiological Pathways Linking Gratitude and Pain

Completed · Not applicable

Conditions studied: Acute Pain, Positive Thinking, Emotions

In brief

The goal of this clinical trial is to compare the effects of a brief gratitude intervention on individuals' psychological and physiological responses to acute pain. Furthermore, these associations will be examined in the context of genetic variations associated with both pain and psychological processes.

Key facts

Study ID

NCT06317844

Run by

Black Hills State University

People needed

145

Starts

2024-09-10

Expected to finish

2025-08-19

Last updated by the study team

2026-04-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• must be pain-free
• must be at least 18 years old

You may not qualify if…

• cardiovascular disease
• Raynaud's disease
• epilepsy
• being pregnant
• having a current injury to or open cut or sore on one's non-dominant hand
• history of fainting or seizures
• history of frostbite in non-dominant hand
• chronic pain conditions (e.g., fibromyalgia, neuropathy, arthritis)
• diabetes
• malignant tumor
• chronic lung disease
• liver disease
• kidney disease
• gastrointestinal diseases
• currently taking opioids

Where it is running

• Black Hills State University — Spearfish, South Dakota, United States

Full record on ClinicalTrials.gov

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