Pilot Study: A Novel Method of Non-Invasive Brain Stimulation (kTMP) to Enhance Motor Function in Chronic Stroke Patients

Completed · Not applicable

Conditions studied: Stroke

In brief

Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities. The goal of this proposal is to provide a first assessment of the feasibility and efficacy of an innovative non-invasive brain stimulation system, kTMP, in the treatment of motor impairment following stroke.

Key facts

Study ID

NCT06317194

Run by

Magnetic Tides

People needed

7

Starts

2025-09-15

Expected to finish

2026-04-30

Last updated by the study team

2026-06-30

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-80 years with stable upper limb motor dysfunction caused by a single ischemic and/or hemorrhagic stroke greater than 6 months prior to recruitment
• Fugl-Meyer Assessment: Upper Extremity (FMA UE) score 20-50
• Motor evoked potentials in a hand muscle when stimulating ipsilesional cortex with suprathreshold single-pulse TMS (MEP+), a proxy of residual corticospinal function.

You may not qualify if…

• Participants with cognitive impairment (MoCA < 20), language impairment that interferes with their ability to adhere to the protocol or to provide informed consent.
• Individuals who are pregnant, have uncontrolled medical problems including but not limited to severe cardiovascular and cardiopulmonary disease, severe alcohol or drug abuse within the past year, or major depression.
• Contraindications related to non-invasive brain stimulation

Where it is running

• Magnetic Tides, Inc. — Berkeley, California, United States

Full record on ClinicalTrials.gov

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