Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(PDT) With Chlorin-e6 in Treating Moderate to Severe Acne
Recruiting now · Phase 2 · Has a placebo group
Conditions studied: Acne, Photodynamic Therapy
In brief
This study aims to evaluate the clinical efficacy, safety and tolerability of a photodynamic therapy(PDT) based on a new photosensitizer, Chlorin-e6, in the treatment of moderate to severe acne. The hypothesis is that the therapy has good efficacy, safety and tolerability.
Key facts
- Study ID
- NCT06311890
- Run by
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
- People needed
- 46
- Starts
- 2024-02-01
- Expected to finish
- 2026-09-30
- Last updated by the study team
- 2024-03-15
Who can join
Age: 18 and older, up to 50. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subject is male or non-pregnant female 18 years of age and younger than 50 years of age.
- Subject has moderate to severe facial acne vulgaris.
- Subject has provided written informed consent.
You may not qualify if…
- People who are taking photosensitive drugs;
- Allergic to any component of the photosensitizer;
- porphyrins or allergies to porphyrins, with a history of photosensitivity;
- Pregnant or lactating women and those planning to become pregnant within 3 months;
- Oral or topical antibiotics, retinoids, glucocorticoids, peroxybenzoyl and other drugs within the past 1 month;
- Have a history of exposure to sunlight in the past 1 month, have received photoelectric treatment in the past 3 months, or have received facial grinding treatment in the past six months;
- are using vasodilators (such as nitroglycerin, etc.), beta blockers (such as metoprolol, etc.), anticoagulants (such as warfarin, etc.) and other drugs that easily cause facial capillary dilatation;
- Patients with facial rosacea, atopic dermatitis, hormone-dependent dermatitis and other facial skin-related diseases;
- Abnormal blood and urine routine, liver and kidney function, diseases of important organs and hematopoietic system that researchers believe are not suitable for clinical trials;
- Patients participating in other clinical trials at the same time.
Where it is running
- Xiyuan Hospital of China Academy of Chinese Medical Sciences Organization — Beijing, China (enrolling)
Full record on ClinicalTrials.gov
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