Topical YR001 Ointment in Adult With Mild to Moderate Atopic Dermatitis

Completed · Phase 2 · Has a placebo group

Conditions studied: Atopic Dermatitis

In brief

This study is to evaluate the safety, tolerability, and pharmacokinetics of YR001 topical ointment in adult patients with mild to moderate atopic dermatitis

Key facts

Study ID

NCT06309355

Run by

Hangzhou Yirui Pharmaceutical Technology Co., Ltd

People needed

35

Starts

2024-06-19

Expected to finish

2025-11-20

Last updated by the study team

2025-12-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Written informed consent obtained from the subject.
• Male or female subject is aged 18 or older.
• Subject has a weight of at least 50 kg and a body mass index (BMI) between 18.0 and 30.0 kg/m2, inclusive.
• An Investigator Static Global Assessment (ISGA) score of 2 (mild) to 3 (moderate) at screening and Baseline.

You may not qualify if…

• Pregnant or lactating women.
• Any skin tattoo, scar, cuts, bruises, or other skin damage, including excessive UV exposure, at the possible IP application sites.
• Patients who have a source of itch solely or significantly from untreatable areas (face, scalp, genitals, palms of hands or soles of feet).
• Have concomitant skin disease or infection (e.g., acne, impetigo) or presence of skin comorbidities in the skin areas to be dosed that may interfere with study assessments and treatment response.
• Participation in another interventional clinical trial (e.g. investigational drug, biological agent, or device) within 30 days or 5 half-lives of investigational agent (whichever is longer) before entering, or during the trial, or previous participation in this clinical trial.

Where it is running

• Encore Medical Research -Boynton Beach — Boynton Beach, Florida, United States
• Encore Medical Research-Hollywood — Hollywood, Florida, United States
• Encore Medical Research-Weston — Weston, Florida, United States
• DelRicht Research — Baton Rouge, Louisiana, United States

Full record on ClinicalTrials.gov

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