Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis

Recruiting now

Conditions studied: Toxoplasmosis

In brief

Toxoplasmosis is a common infection whose clinical severity can sometimes justify admission to intensive care, especially in immunocompromised patients. This study should make it possible to evaluate the impact of different anti-infective treatment regimens and to highlight clinical-biological and prognostic differences depending on the type of underlying immunosuppression.

Key facts

Study ID

NCT06305468

Run by

Assistance Publique - Hôpitaux de Paris

People needed

200

Starts

2024-08-01

Expected to finish

2026-04-01

Last updated by the study team

2025-01-28

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patient hospitalized in intensive care
• At least 1 organ failure (SOFA> or =2)
• PCR toxoplasmosis on CSF, blood, BAL, or bone marrow positive within 7 days before or after admission to ICU

You may not qualify if…

• Post-mortem diagnosis
• Primary outcome not available
• Patient living informed and not opposed to the reuse of their data in this research.

Where it is running

• Cochin hospital — Paris, France, France (enrolling)

Full record on ClinicalTrials.gov

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