Treatment of Premature Ovarian Insufficiency Using Bone Marrow Cells

Recruiting now · Not applicable

Conditions studied: Premature Ovarian Insufficiency

In brief

investigator is doing single armed clinical interventional study to treat premature ovarian insufficiency with autologous bone marrow derived mononuclear cells to be given systematically and locally to the ovaries under ultrasound guidance with experienced gynecologist and to look for the results including: laboratory evidence through hormonal study ultrasound proof of ovarian follicle development. premature ovarian insufficiency is characterized by early loss of ovarian function (less than 40 years of age) manifested by menstrual irregularity or amenorrhea with elevated levels of gonadotropin hormones and low estrogen and anti-Mullerian hormone. Autologous use of stem cells from bone marrow are alternative safe minimal manipulative products that can provide a solution to this clinical problem without the need for oocyte donation program.

Key facts

Study ID

NCT06302543

Run by

abdulmajeed hammadi

People needed

10

Starts

2024-03-01

Expected to finish

2026-03-10

Last updated by the study team

2025-08-05

Who can join

Age: 30 and older, up to 60. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• clinical diagnosis of premature Ovarian insufficiency.
• ineffective hormonal therapy.
• biochemical evidence of high gonadotropins.

You may not qualify if…

• solid or hematological malignancies.
• bleeding disorders.
• rejection of the procedure.

Where it is running

• Ministry of Health — Baghdad, Iraq (enrolling)

Full record on ClinicalTrials.gov

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