Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Tooth Mobility, Injectable Platelet-rich Fibrin
In brief
One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which makes the results difficult to generalize.
Key facts
- Study ID
- NCT06302296
- Run by
- Hama University
- People needed
- 14
- Starts
- 2025-12-20
- Expected to finish
- 2026-07-15
- Last updated by the study team
- 2025-09-15
Who can join
Age: 18 and older, up to 26. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- The patient's age (18-26). Severe or very severe irregularity of the upper incisors greater than (7 mm) according to Little's index, so it is recommended to extract the upper first premolar.
- Class I or Class II malocclusion, first model according to Angle, with skeletal class I or II and a normal or mild vertical growth pattern.
- All permanent upper teeth, up to the first molar, are present, with the possibility of attaching brackets to all teeth in a correct position.
- The patient has good oral health.
You may not qualify if…
- • The presence of any systemic disease that affects orthodontic dental movement.
- Severe malalignment of one of the teeth (palatal quadrant, ectopic canine, ectopic premolar).
- The patient has undergone previous orthodontic treatment.
- The patient is subject to any drug treatment that may affect orthodontic dental movement (cortisone, non-steroidal anti-inflammatory drugs).
- The patient has poor oral health.
- Commitment to periodic follow-up appointments.
Where it is running
- Fadi Jnaid — Hama, Syria (enrolling)
Full record on ClinicalTrials.gov
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