The Pattern of Dry Eye Disease After Cataract Surgery
Recruiting now
Conditions studied: Dry Eye Disease, Cataract, Ocular Surface Disease
In brief
This study is designed to explore dry eye disease (DED) pattern: ocular surface, corneal morphological changes, patients' subjective assessment of DED and their correlations with ocular surface inflammation, pain biomarkers after cataract surgery according to ocular surface lubrication with artificial tears during long-term follow-up.
Key facts
- Study ID
- NCT06298890
- Run by
- Lithuanian University of Health Sciences
- People needed
- 100
- Starts
- 2024-03-01
- Expected to finish
- 2027-09-01
- Last updated by the study team
- 2024-03-07
Who can join
Age: 50 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Cataract patients from 50 to 90 years old who underwent uncomplicated phacoemulsification performed by one (and same) experienced surgeon.
- Patients with no underlying ocular surface diseases (keratitis, keratoconjunctivitis and others).
- Patients who previously did not undergo any ophthalmic surgery.
You may not qualify if…
- Patient expressed his wish to not participate in the study or discontinue it when already enrolled.
- Severe dry eye disease diagnosed with OSDI/DEQ-5 and at least one of the following tests: TBUT less than 10 seconds, tear osmolarity higher than 308 mOsm/l or positive corneal staining.
- Glaucoma.
- Diabetes mellitus.
- Systemic connective tissue disease, autoimmune disease.
- Neurologic conditions including stroke, Bell's palsy, Parkinson's, trigeminal nerve dysfunction.
- Patients who underwent refractive surgery (LASIK or PRK).
- Contact lens users.
- One or more of the following concomitant medications: psychiatric medicines, antihistamines and/or hormonal replacement.
- Patients who are already regularly using topical drops or ointments.
Where it is running
- Lithuanian University of Health Sciences — Kaunas, Lithuania (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.