Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.

Recruiting now · Phase 4

Conditions studied: Crohn Disease, Ulcerative Colitis

In brief

The purpose of this study is to compare how effective and how tolerable two different bowel preparation laxatives are for colonoscopy. The aim is to compare oral sulfate solution (OSS) to another laxative called 2L polyethylene glycol (PEG) solution to see which is more effective and more tolerable by individuals with IBD (Crohn's disease or Ulcerative colitis).

Key facts

Study ID

NCT06298461

Run by

University of Manitoba

People needed

418

Starts

2024-07-04

Expected to finish

2026-05-01

Last updated by the study team

2025-01-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Crohn's disease or ulcerative colitis patients scheduled or about to be scheduled for colonoscopy.
• Age > 18 years
• Out-patients

You may not qualify if…

• Prior subtotal or total colorectal resection
• Contraindications to use of 2L polyethylene glycol (2L-PEG) or Oral Sulfate Solution (OSS): Known renal insufficiency, congestive heart failure, cirrhosis, severe electrolyte imbalance.
• Colonoscopy being repeated because of poor preparation in the preceding six months.
• Allergies to the employed bowel preparations
• Toxic megacolon, ileus, suspected or diagnosed bowel obstruction.
• IBD patients thought to be too sick to undergo a full colonoscopy preparation in the opinion of the investigator/treating physician; hospitalized crohn's disease or ulcerative colitis patients.
• Pregnancy

Where it is running

• University of Manitoba — Winnipeg, Manitoba, Canada (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.