Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures
Running, not enrolling · Not applicable
Conditions studied: Tobacco Use, Cigarette Smoking, Nicotine Dependence
In brief
Characterize effects of relighting on smoke toxicant deliveries and subjective smoking measures. This will be a within-subject comparison in a single experimental group of 30 smokers who report engaging in relighting behaviors. We will assess smoking intensity for relit and non-relit (i.e., smoked continuously without relighting) cigarettes in the natural environment and will conduct in-clinic measurements of smoking topography and subjective responses for relit and non-relit cigarettes. Information on relighting patterns and smoking topography collected from each participant will be used to compare machine-measured smoke yields of key harmful constituents when their usual cigarettes are smoked with and without relighting. Hypothesis: Relit cigarettes will produce higher levels of toxicants than non-relit cigarettes.
Key facts
- Study ID
- NCT06295757
- Run by
- Masonic Cancer Center, University of Minnesota
- People needed
- 26
- Starts
- 2024-10-12
- Expected to finish
- 2028-01-01
- Last updated by the study team
- 2026-07-13
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Smoking at least 10 cigarettes/day for at least 1 year (confirmed by CO > 8 ppm or NicAlert test of 6)
- Engaging in relighting for at least half of their CPD
- No smoking quit attempts in the past month nor intentions to quit in the next month
- Stable medical or psychiatric conditions with systolic blood pressure < 160, diastolic blood pressure < 100 and heart rate < 105 bpm
You may not qualify if…
- Participant with current or recent alcohol or drug abuse problems, use of substances of abuse (other than marijuana due to high prevalence of co-use) within the past month
- Currently trying or planning to quit smoking in the next month
- Planning to become pregnant, pregnant or breastfeeding. Pregnancy exclusion will be confirmed through a urine test.
Where it is running
- Irina Stepanov, PhD — Minneapolis, Minnesota, United States
Full record on ClinicalTrials.gov
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