Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

Running, not enrolling · Phase 2 · Has a placebo group

Conditions studied: Ulcerative Colitis

In brief

The goal of this study is to learn if emvistegrast (formerly GS-1427) is effective in treating participants with moderate to severe ulcerative colitis. The study will compare participants in different treatment groups treated with emvistegrast with participants treated with placebo. The primary objective of this study is to assess the efficacy of emvistegrast, compared with placebo control, in achieving clinical response at Week 12.

Key facts

Study ID
NCT06290934
Run by
Gilead Sciences
People needed
228
Starts
2024-03-27
Expected to finish
2028-04-01
Last updated by the study team
2026-04-09

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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