A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

Recruiting now · Not applicable

Conditions studied: Anemia, Sickle Cell

In brief

The goal of this clinical trial is to evaluate the impact of SCThrive (a behavioral self-management intervention) on patient activation, self-management behaviors, daily functioning, and emergency room visits in 260 adolescents and young adults with sickle cell disease (SCD) ages 13-21 receiving care at 1 of 4 pediatric SCD clinics. The main question\[s\]it aims to answer are: * Does SCThrive improve patient activation? * Does SCThrive improve self-management behaviors, daily functioning, and decrease emergency room visits? * Are any improvements maintained 3 months after treatment? Participants will complete self-management related surveys before, after, and 3 months following their participation in an 8- week, virtual group intervention with an accompanying mobile app (SCThrive). Researchers will compare outcomes for participants who receive SCThrive and participants who receive uniform standard care (SCHealthED which = standard of care plus SCD educational text messages) to see if there are differences in patient activation, self-management behaviors, daily functioning, and emergency room visits.

Key facts

Study ID

NCT06290401

Run by

Children's Hospital Medical Center, Cincinnati

People needed

310

Starts

2025-02-03

Expected to finish

2028-06-30

Last updated by the study team

2026-05-11

Who can join

Age: 13 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient of a participating SCD Clinic
• Confirmed diagnosis of SCD
• 13-21 years of age

You may not qualify if…

• Another chronic disease (which would complicate measurement of patient activation)
• Non-English-speaking
• Cognitive or psychiatric disorder that the physician or study therapists believe would impair study participation.

Where it is running

• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States (enrolling)
• Nemours Children's Health — Wilmington, Delaware, United States
• Children's Healthcare of Atlanta — Atlanta, Georgia, United States
• Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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