Enteral Feeding of Fibre to Improve Microbiota

Recruiting now · Not applicable

Conditions studied: Bowel Dysfunction, Colon Disease, Ileum--Diseases

In brief

Following surgical removal of diseased bowel, patients often require a temporary redirection of bowel contents to a stoma, to allow healing prior to re-joining of the remaining bowel at a later date. Some patients may experience complications, either during or after reversal surgery, and this may be due to changes in the 'friendly' bacteria that live in our bowels. Previous research shows that the distal section of bowel that is non-functioning undergoes tissue-wasting and the 'friendly' bacteria that help our digestion die. Data shows that patients that have a reduction in their microflora are more likely to experience side effects. This study investigates a method of replenishing the microflora prior to surgery.

Key facts

Study ID

NCT06288464

Run by

Lancashire Teaching Hospitals NHS Foundation Trust

People needed

15

Starts

2023-01-09

Expected to finish

2025-12-01

Last updated by the study team

2025-04-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Any individual that has been identified for distal (stoma) feeding that is able to understand verbal and written English to provide informed consent.
• Participants must be undergoing ileostomy or colostomy reversal surgery.

You may not qualify if…

• Not undergoing ileostomy or colostomy reversal.
• Persons who might not adequately understand verbal explanations or written information given in English

Where it is running

• Lancashire Teaching Hospitals NHS — Preston, Lancashire, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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