Behavioral and Cognitive Predictors of Persistent Pain and Opioid Misuse in Chronic Pain

Recruiting now

Conditions studied: Chronic Back Pain

In brief

Chronic lower back pain (CLBP) affects approximately 20% of the global population. The study objective is to determine if impulsivity, inhibitory control, drug choice, and/or cognitive distortions predict opioid misuse and disability in patients with chronic pain. This is a prospective consented cross-sectional study characterizing behavioral and cognitive phenotypes using both patient-reported survey measures and cognitive testing. Outcome measures include correlations between impulsivity measures, opioid drug choice responses and cognitive distortion scores, and risk for opioid misuse (Primary outcomes: COMM scores, SOAPPR scores). Secondary outcomes is BPI measurement. A Certificate of Confidentiality will provide additional protections for participants.

Key facts

Study ID

NCT06288282

Run by

Icahn School of Medicine at Mount Sinai

People needed

130

Starts

2023-12-20

Expected to finish

2025-12-01

Last updated by the study team

2025-06-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• With diagnoses related to chronic lower back pain
• Age above 18yrs
• Non pregnant

You may not qualify if…

• Cancer pain

Where it is running

• Mount Sinai Pain management centers — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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