Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
Recruiting now · Not applicable
Conditions studied: PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
In brief
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD). Prolonged exposure (PE) and crisis response plan (CRP) have demonstrated empirical support for reducing suicide attempts as compared to treatment as usual. However, no studies to date have assessed their effectiveness when used in combination. In light of this knowledge gap, the primary objective of this study will be to test the effectiveness of PE augmented with CRP as compared to PE with care as usual (self-guided treatment plan), an active comparator, for the reduction of suicide ideations and attempts for individuals with comorbid PTSD.
Key facts
- Study ID
- NCT06285708
- Run by
- Ohio State University
- People needed
- 100
- Starts
- 2024-02-26
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-06-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Current diagnosis of PTSD or subthreshold PTSD; ability to speak and understand the English language; and ability to complete the informed consent process.
You may not qualify if…
- Substance use disorder requiring medical management; imminent suicide risk warranting inpatient hospitalization or suicide-focused treatment; and impaired mental status that precludes the ability to provide informed consent (e.g., intoxication, psychosis, mania).
Where it is running
- The Ohio State University — Columbus, Ohio, United States (enrolling)
Full record on ClinicalTrials.gov
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