Quality of Life and Gut Health in Pediatric Patients With Cystic Fibrosis

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Cystic Fibrosis in Children

In brief

The aim of the present study is to investigate the effect of probiotic supplementation on GI related quality of life, through a randomised placebo-controlled clinical trial. Moreover, the invetigators wish to study CF microbiota and intestinal inflammation in the setting of probiotic supplementation and newly started treatment with a highly effective CF-specific treatment, elexacaftor-tezacaftor-ivacaftor (ETI). The proposed project has the potential to increase QoL and decrease GI morbidity in children with CF. If successful, the results of this study can contribute to alter the care of CF patients by including supplementation of probiotics in routine CF care. Morever, the study can provide much needed insights to GI microbiota and inflammation in pediatric CF patients.

Key facts

Study ID
NCT06284577
Run by
Oslo University Hospital
People needed
40
Starts
2024-01-02
Expected to finish
2027-07-01
Last updated by the study team
2024-06-13

Who can join

Age: 2 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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