Risk Factors for Neuroendocrine Neoplasms
Recruiting now
Conditions studied: Neuroendocrine Neoplasm of Lung, Neuroendocrine Neoplasm of Gastrointestinal Tract (Disorder)
In brief
Recent studies show an increase in neuroendocrine neoplasms, especially for the digestive tract. Previous studies suggest various risk factors that were observed for various tumor sites, e.g. a family history of cancer, tobacco and alcohol consumption as well as metabolic disorders including diabetes and obesity. A risk factor that has been little studied to date is depressive disorders, which could increase the risk of neuroendocrine neoplasms either independently or through associated risk behaviors and/or antidepressant medication. The aim of this study is to identify risk factors for neuroendocrine neoplasms based on a case-control study in order to better understand the increase of neuroendocrine neoplasms in recent decades. The study is based on a record linkage of data from the Bavarian Cancer Registry and data from the Bavarian Association of Statutory Health Insurance Accredited Physicians. While the data from the Bavarian Cancer Registry enables the identification of neuroendocrine neoplasms on the basis of histopathological findings and thus is the basis for selecting cases, the claims data from the Bavarian Association of Statutory Health Insurance Accredited Physicians provides the source population as well data on diagnoses and thus enables the investigation of risk factors.
Key facts
- Study ID
- NCT06282016
- Run by
- Bavarian Cancer Registry
- People needed
- 14250
- Starts
- 2025-05-15
- Expected to finish
- 2026-08-01
- Last updated by the study team
- 2026-01-07
Who can join
Age: any. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Persons with a statutory health insurance (about 85% of the population) and at least one outpatient physician contact in Bavaria between 2021 and 2023
- Residence in Bavaria
You may not qualify if…
- None
Where it is running
- Bavarian Cancer Registry, Bavarian Health and Food Safety Authority — Nuremberg, Bavaria, Germany (enrolling)
Full record on ClinicalTrials.gov
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