A Study of RGT001-075 in Participants With Obesity or Overweight With Weight-Related Comorbidities

Completed · Phase 2 · Has a placebo group

Conditions studied: Obesity

In brief

The main purpose of this study was to evaluate the safety and tolerability of RGT001-075 in healthy participants with obesity

Key facts

Study ID

NCT06277934

Run by

Regor Pharmaceuticals Inc.

People needed

73

Starts

2024-03-08

Expected to finish

2024-08-13

Last updated by the study team

2025-08-07

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 and ≤ 75 years
• Have a BMI ≥27 kg/m² and ≤ 45 kg/m²
• Have had a stable body weight for the 3 months prior to randomization

You may not qualify if…

• Have obesity induced by other endocrinologic disorders or diagnosed monogenetic or syndromic forms of obesity
• Have a prior or planned surgical treatment for obesity
• Have or plan to have endoscopic and/or device-based therapy for obesity
• Have any prior diagnosis of diabetes
• Have an electrocardiogram (ECG) with abnormalities
• Have a history of Major Depressive Disorder (MDD) or other severe psychiatric disorders within the last 2 years
• Have a history of suicide attempt.

Where it is running

• Velocity Clinical Research — Los Angeles, California, United States
• Velocity Clinical Research — Valparaiso, Indiana, United States
• Velocity Clinical Research — Omaha, Nebraska, United States
• Velocity Clinical Research — Vestal, New York, United States
• Velocity Clinical Research — Durham, North Carolina, United States
• Velocity Clinical Research — Cleveland, Ohio, United States
• Velocity Clinical Research — Medford, Oregon, United States
• Velocity Clinical Research — East Greenwich, Rhode Island, United States
• Velocity Clinical Research — Dallas, Texas, United States
• Velocity Clinical Research — West Jordan, Utah, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.