Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test
Running, not enrolling · Not applicable
Conditions studied: Mild Traumatic Brain Injury
In brief
This study aims to compare symptom provocation, physiologic response, and rate of perceived (RPE) between the Buffalo Concussion Treadmill Test (BCTT) and a Modified Dynamic Exertion (mEXiT) test after sport related concussion in adolescents aged 14-17. Participants will be enrolled at their initial concussion clinical visit within 14 days of their injury, and randomly assigned to either the BCTT or mEXiT group. Participants will complete a single visit.
Key facts
- Study ID
- NCT06276660
- Run by
- University of Pittsburgh
- People needed
- 60
- Starts
- 2024-03-05
- Expected to finish
- 2026-09-30
- Last updated by the study team
- 2026-02-17
Who can join
Age: 14 and older, up to 17. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosed with a sport related concussion within 14 days of injury
- Participants referred to exertion therapy after a trained clinician from University of Pittsburgh Medical Center (UPMC) Sports Medicine Concussion Program has interpreted neurocognitive, vestibular, and clinical interview outcomes and determined the participant is capable of completing structured exercise.
You may not qualify if…
- Medically cleared from a previous concussion within the past 6 months
- More than 2 previous concussions (excluding current injury)
- History of brain surgery or traumatic brain injury (TBI) (based on Glasgow Coma Scale of <13)
- History of neurological disorder (seizure disorder, epilepsy, brain tumors or malformations)
- Current history of pre-existing vestibular disorder or oculomotor condition
- Currently taking antidepressant, anticoagulant, beta-blocker, or anticonvulsant prescription medications
- Incapable of treadmill running up to 5.5 miles per hour (mph) and 4.5 mph for males and females respectively (self-reported).
- Diagnosed with a cardiac, peripheral, or cerebrovascular disease (type 1 or 2 diabetes, or renal disease.
- Experienced chest pain or shortness of breath while at rest or with mild exertion.
- Lose balance because of dizziness or have lost consciousness (aside from concussion) from exertion
- Currently have (or have had within the past 12 months) a bone, joint, or soft tissue (muscle, ligament, or tendon) problem that could be made worse by physical activity
- Been told by a doctor to only conduct physical activity under medical supervision.
Where it is running
- UPMC/Univ of Pgh Sports Medicine Concussion Research Program — Pittsburgh, Pennsylvania, United States
Full record on ClinicalTrials.gov
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