Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation?

Recruiting now · Not applicable

Conditions studied: Alveolar Ridge Preservation, Dental Extraction, Bone Graft

In brief

The purpose of the study is to compare a new grafting material for alveolar ridge preservation to a commonly used and well studied material. Alveolar ridge dimensions as well as histology will be compared.

Key facts

Study ID

NCT06275789

Run by

Nova Southeastern University

People needed

30

Starts

2024-01-26

Expected to finish

2026-06-01

Last updated by the study team

2025-09-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients in good health
• Require the extraction of at least one premolar or molar with future implant placement
• Sufficient keratinized gingiva (equal or more than 2mm prior to extraction),
• No more than 3mm of buccal bone loss
• Flapless extraction possible
• Full mouth plaque index of less than 25%

You may not qualify if…

• Nicotine consumption equivalent to or more than 10 cigarettes per day
• Electronic cigarette usage
• A history of irradiation of head and neck area
• Immunodeficiency disease
• Uncontrolled systemic health problems (hypertension crisis 180/120, hyperthyroidism, diabetes with HbA1c over 7, recent history of stroke, cancer) History of medications that affect bone remodeling process (bisphosphonates, RANK-L inhibitors)
• Previous adverse reaction to the biomaterials used
• Pregnancy/lactation, or those who are trying to become pregnant.
• Active uncontrolled or untreated periodontal disease
• Periapical lesions greater than 1 cm and soft tissue pathology

Where it is running

• Nova Southeastern University — Fort Lauderdale, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

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