RChildUV:Study on Non-infectious Chronic Uveitis in Pediatric Age
Recruiting now
Conditions studied: Uveitis
In brief
Uveitis is an inflammatory disease of the uvea, one of the highly vascularized fundamental structures of the eye. It is a rare condition in children, with an incidence in the pediatric population ranging from 2% to 14% of all uveitis cases. The diagnosis and management of patients with uveitis rely on a multidisciplinary approach involving an ophthalmologist, a rheumatologist, and an infectious disease specialist to establish the correct diagnosis and assess the involvement of other organs. In Italy, there is no national or regional registry for non-infectious chronic uveitis as per the Prime Ministerial Decree (DPCM) of March 3, 2017 (Identification of surveillance systems and registries for mortality, tumors, and other diseases). However, many clinical centers adopt data recording systems to evaluate the quality of care and to study diseases and outcomes. The Universitary Hospital Meyer Institute Research Hospital (IRCCS) is a national referral center for managing these pediatric cases of non-infectious chronic uveitis, estimated to constitute 95% of all pediatric uveitis cases
Key facts
- Study ID
- NCT06273748
- Run by
- Meyer Children's Hospital IRCCS
- People needed
- 290
- Starts
- 2022-02-10
- Expected to finish
- 2032-05-02
- Last updated by the study team
- 2026-03-27
Who can join
Age: 1 and older, up to 16. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- diagnosis of non-infectious chronic uveitis before the age of 16;
- signed informed consent form.
You may not qualify if…
- Patients with a diagnosis of infectious uveitis
- history of malignant pathology,
- history of demyelinating pathology,
- history of cerebral vasculitis
Where it is running
- Department of Pediatric Rheumatology, Kocaeli University, — Kocaeli, Turkey (Türkiye) (enrolling)
- The Children's Hospital Corporation d/b/a Boston Children's Hospital — Boston, Massachusetts, United States (enrolling)
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States (enrolling)
- ATTIKON General Hospital — Athens, Greece (enrolling)
- Meyer Children's Hospital IRCCS — Florence, Firenze, Italy (enrolling)
- Department of Medical of Health Sciences, Magna Grecia University — Catanzaro, Italy (enrolling)
- Dipartimento di Immunologia e Reumatologia Pediatrica, Ospedale Vito Fazzi — Lecce, Italy (enrolling)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico SC Pediatria e Immunoreumatologia PI — Milan, Italy (enrolling)
- IRCCS materno infantile Burlo Garofolo — Trieste, Italy (enrolling)
- Children's Mercy Kansas City Division of Rheumatology, Division of Rheumatology — Kansas City, Kansas, United States (enrolling)
- Unità di Immunologia e Reumatologia, Ospedale Pediatrico Regina Margherita, AOU Città della Salute e della scienza di Torino — Torino, Italy
- Unità di Reumatologia ed Immunologia Pediatrica dell'Ospedale Fatebenefratelli Sacco di Milano — Milan, Italy
- University fo Gent — Ghent, Belgium
- - UOSD Reumatologia Pediatrica Dipartimento di Salute della Donna e del Bambino Azienda Ospedale Università di Padova — Padova, Italy
- Clinica Pediatrica, IRCCS Policlinico San Matteo — Pavia, Italy
- Department of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari — Bari, Italy
- Ospedale Spedali Civili di Brescia — Brescia, Italy
- IRCCS Ospedale Pediatrico Bambino Gesù Dipartimento Reumatologia — Roma, Italy
- Santa Maria Goretti Hospital — Roma, Italy
Full record on ClinicalTrials.gov
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