Real-World HRU and Costs in DLBCL Pts With Tisa-cel and Axi-cel, a Medicare Study.
Completed
Conditions studied: Diffuse Large B-cell Lymphoma
In brief
This was a retrospective non-interventional cohort study design using the Centers for Medicare and Medicaid Services (CMS) 100% Medicare data (2015Q1-2020Q4). Eligible adult patients with r/r DLBCL who were treated with CAR-T therapy were identified from the CMS 100% Medicare data. Patients who received chimeric antigen receptor modified T cell (CAR-T) therapy were further classified into tisa-cel and axi-cel cohorts based on the type of CAR-T treatment received. The index date was defined as the date of tisa-cel or axi-cel therapy administration. Baseline period was defined as three months prior to the index date. Study period was defined from the index date to the end of health plan coverage based on insurance enrollment file or death, whichever occurred earlier.
Key facts
- Study ID
- NCT06271369
- Run by
- Novartis Pharmaceuticals
- People needed
- 613
- Starts
- 2022-08-11
- Expected to finish
- 2023-02-15
- Last updated by the study team
- 2024-02-21
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients had at least one International Classification of Diseases, 10th Revision (ICD-10) diagnosis code for DLBCL.
- Patients received CAR-T therapy, including both tisa-cel and axi-cel, following DLBCL diagnosis. The administration date of CAR-T therapy was defined as the index date.
- Patients were at least 18 years of age as of the index date.
- Patients had at least three months of continuous health plan enrollment before the index date.
You may not qualify if…
- Patients who had a medical claim associated with a clinical trial within one month before and after the index date.
- Patients who had zero cost on index date for CAR-T infusion.
Where it is running
- Novartis — East Hanover, New Jersey, United States
Full record on ClinicalTrials.gov
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