Effect of Antioxydant-enriched Media on Blastocyst Euploidy Rates.

Recruiting now · Not applicable

Conditions studied: Infertility, In Vitro Fertilization

In brief

One of the most sensible factors in IVF culture conditions is the susceptibility of gametes and embryos to an induced increase in reactive oxidative species (ROS) caused by the artificial environment. This study aims to evaluate the impact of using antioxidant-supplemented media during culture to evaluate embryo ploidy rates in a prospective randomized trial using sibling oocytes.

Key facts

Study ID

NCT06261671

Run by

ART Fertility Clinics LLC

People needed

500

Starts

2024-02-01

Expected to finish

2025-12-31

Last updated by the study team

2025-02-21

Who can join

Age: 18 and older, up to 43. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients undergoing assisted reproductive technology cycles when ICSI is indicated.
• Patients when Iin vitto fertilization (IVF) is also performed will be included as far as there are enough oocytes for ICSI randomization. However, IVF oocytes will not be used for the study.
• Maternal age 18-43 years old.
• PGT-A cycles with only trophectoderm biopsies on day 5/6/7.
• Patients with more than 6 COCs expected for ICSI.
• Body mass index <35.
• Fresh and frozen ejaculated sperm.

You may not qualify if…

• PGT-M cycles
• Fresh and frozen testicular sperm.

Where it is running

• ART Fertility Clinics LLC — Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates (enrolling)

Full record on ClinicalTrials.gov

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