Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium
Recruiting now · Not applicable
Conditions studied: Stroke, Acute Cerebrovascular Accident, Transient Ischemic Attack, Death, Atrial Fibrillation Recurrent
In brief
Atrial fibrillation (AF) is the cause of 20% of strokes, and the risk of stroke in a person suffering from this arrhythmia increases by 5 times. Ischemic stroke in patients with AF is often fatal and, compared with stroke of other etiology, leads to the most pronounced disability and more often recurs. Accordingly, the risk of death in patients with AF-related stroke is 2 times higher, and treatment costs increase 1.5 times. The main interventional method of treating AF, available in most medical institutions, is the use of radio frequency and/or cryoenergy to eliminate destructive damage to the left atrium (LA). The aim of this study is to compare two different interventional methods and identify predictors of recurrence in patients with persistent and long-term AF.
Key facts
- Study ID
- NCT06253000
- Run by
- Bakulev Scientific Center of Cardiovascular Surgery
- People needed
- 158
- Starts
- 2023-06-10
- Expected to finish
- 2026-12-30
- Last updated by the study team
- 2026-07-20
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age over 18 years old;
- Atrial fibrillation resistant to antiarrhythmic therapy;
- Persistent and long-persisting form of atrial fibrillation;
- The patient's consent to participate in the study.
You may not qualify if…
- Age under 18 and over 80 years old;
- The presence of another cardiac pathology requiring surgical treatment;
- Congenital heart defects;
- Previous "open" cardiac surgery;
- Bone marrow diseases;
- Pathology of the blood coagulation system;
- The left ventricular ejection fraction is less than 40%;
- Moderate to severe renal insufficiency (creatinine clearance <50 ml/min);
- Drug-resistant hypertension (despite hypotensive therapy);
- Organically altered mitral valve;
- There are reasons to assume that the patient will not show up for subsequent visits (control points of the study) for various reasons;
- The patient's participation in another clinical trial.
Where it is running
- Bakulev National Medical Research Center for Cardiovascular Surgery — Moscow, Russia (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.