Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens

Recruiting now · Not applicable

Conditions studied: Lung Cancer, Lymph Node Metastasis, Pathologic Processes

In brief

Lung cancer patients undergoing upfront surgery, highly benefit from a systematic lymph node dissection in the mediastinum and in the surgical specimens. The latter is performed by the pathologist. Developing a standardized technique to dissect the lobectomy specimen has the potential of maximizing the retrieval of all N1 stations lymph nodes. The investigators believe that the adoption of such technique will improve lung cancer staging and identify a higher number of patients that qualify for adjuvant therapies.

Key facts

Study ID

NCT06252129

Run by

Brigham and Women's Hospital

People needed

160

Starts

2024-07-26

Expected to finish

2027-12-01

Last updated by the study team

2026-03-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects with a lung nodule or mass who are eligible to undergo a lobectomy.
• Subject without any metastasis present.
• Subjects who have peripheral lung nodule location
• Subjects must be 18 years of age or older.

You may not qualify if…

• Subjects who received preoperative chemotherapy or radiotherapy.
• Subjects who have a lung nodule located in a central location. Central tumors are defined by those infiltrating the lobar airway.

Where it is running

• Brigham and Womens Hospital — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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