Evaluation of Sinus Augmentation Bone Healing Using Autograft and Xenograft Compared to Xenograft Alone

Running, not enrolling · Not applicable

Conditions studied: Maxillary Sinus Floor Augmentation, Dental Implant, Bone Substitute, Autogenous Bone Graft

In brief

To evaluate bone healing at 4 months after lateral sinus augmentation with a 4:1 ratio of autologous bone and xenograft or xenograft alone. A radiographic volumetric, histomorphometric, and histologic analysis.

Key facts

Study ID

NCT06247098

Run by

Tufts University

People needed

10

Starts

2024-09-01

Expected to finish

2028-05-01

Last updated by the study team

2026-01-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients of Tufts School of Dental Medicine (TUSDM)
• Two stage sinus augmentations with <5mm (Zinner, Small 2004) residual bone height in need of augmentation for implant placement
• Full maxillary edentulism or Kennedy class I or III
• 18 to 100 year old

You may not qualify if…

• Adults unable to consent (cognitively impaired adults)
• Those who self-report as pregnant or breastfeeding
• Wards of the state
• Non-Viable neonates
• Neonates of uncertain viability
• < 18 years of age
• Refusal to participate
• Prior medical condition causing complications in bone metabolism
• Osteoporosis
• History of/or current chemotherapy
• History of/or current head and neck radiation
• Current heavy smoking > 10 cigarettes/day
• Self-reported pregnancy or lactation
• Previous history of sinus elevation procedure
• Existing sinus pathology or pathology discovered at time of sinus augmentation or implant placement
• Absence of autogenous donor site

Where it is running

• Tufts University School of Dental Medicine — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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