Studies of Phenotypic and Functional Characteristics of Circulating Neutrophil Subpopulations in Patients With Lung Cancer
Recruiting now
Conditions studied: Lung Cancer
In brief
The objective is to study the phenotypic, functional and metabolomic characteristics of neutrophils circulating subpopulations in lung cancer patients, and to compare them to a control group of healthy volunteers. A blood sample will be taken before the first treatment session for the lung cancer patient and a second blood sample will be taken during the first evaluation visit. The investigators hypothesize that there may be different circulating neutrophil subpopulations in patients with metastatic non-small cell lung cancer (NSCLC) involved in tumor progression and resistance to immunotherapy.
Key facts
- Study ID
- NCT06244355
- Run by
- Assistance Publique - Hôpitaux de Paris
- People needed
- 100
- Starts
- 2024-02-12
- Expected to finish
- 2027-12-01
- Last updated by the study team
- 2026-03-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may not qualify if…
- Tuberculosis or other acute or chronic bacterial infections
- Chronic progressive viral infections (Hepatitis B and C, HIV)
- Previous or ongoing chemotherapy
- Impossibility of giving the subject informed information.
- Opposition to the research.
- Participation in another research study with an exclusion period still in progress at pre-inclusion (possible inclusion in an observational study)
- Vulnerable individual (pregnant, parturient or breastfeeding woman), persons under guardianship or curatorship, or deprived of liberty by a judicial or administrative decision)
- Patients benefiting from the AME
Where it is running
- Assistance Publique - Hôpitaux de Paris (AP-HP) - Cochin Hospital - Pneumology unit — Paris, Île-de-France Region, France (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.