The Safety and Efficacy of Autologous Transfusion in Spinal Surgery for Lung Cancer With Spinal Metastasis
Recruiting now · Not applicable
Conditions studied: Spinal Metastases, Blood Transfusion Complication, Lung Cancer, Surgery, Autologous Blood Transfusion
In brief
The goal of this single-center prospective randomized controlled trial is to test and compare the safety and effectiveness of autologous blood transfusion in spinal surgery for lung cancer spinal metastases. The main questions it aims to answer are: * Does autologous blood transfusion increase the incidence of new metastases? * Does autologous blood transfusion affect postoperative hemoglobin levels and the number of circulating tumor cells in the blood? * Can autologous blood transfusion reduce the rate of allogeneic transfusion during and after surgery for spinal metastases?
Key facts
- Study ID
- NCT06244264
- Run by
- Guangdong Provincial People's Hospital
- People needed
- 118
- Starts
- 2024-03-15
- Expected to finish
- 2027-12-31
- Last updated by the study team
- 2024-07-12
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- The age range is 18-75 years old;
- The pathological diagnosis was lung cancer and spinal metastatic tumor;
- Expected survival > 3 months, can tolerate surgery;
- Unstable spine; And/or spinal cord nerve compression, nerve function; Progressive decline, palliative spinal open decompression surgery
- Patients with intraoperative/postoperative Hb<90 g/L or other conditions requiring blood transfusion
You may not qualify if…
- Serious heart dysfunction or heart failure, diagnosed blood system diseases, coagulation disorders;
- Severe renal insufficiency or need hemodialysis treatment;
- Sepsis or septicemia;
- Unable to obtain consent from the patient or family.
Where it is running
- Guangdong provincial people's hospital — Guangzhou, Guangdong, China (enrolling)
Full record on ClinicalTrials.gov
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