A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF
Recruiting now · Phase 2 · Has a placebo group
Conditions studied: Cystic Fibrosis
In brief
This is the first-in-human study with RCT2100 and is designed to provide safety and tolerability data for future clinical studies.
Key facts
- Study ID
- NCT06237335
- Run by
- ReCode Therapeutics
- People needed
- 192
- Starts
- 2024-02-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2026-01-16
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
Where it is running
- University Hospital Southampton — Southampton, United Kingdom (enrolling)
- University of Arizona — Tucson, Arizona, United States (enrolling)
- Stanford University — Palo Alto, California, United States (enrolling)
- UCSD — San Diego, California, United States (enrolling)
- National Jewish Health — Denver, Colorado, United States (enrolling)
- Emory University — Atlanta, Georgia, United States (enrolling)
- Boston Children's Hospital — Boston, Massachusetts, United States (enrolling)
- New York Medical College — Valhalla, New York, United States (enrolling)
- The University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States (enrolling)
- Oregon Health & Science University — Portland, Oregon, United States (enrolling)
- University of Pittsburgh — Pittsburgh, Pennsylvania, United States (enrolling)
- UT Southwestern Medical Center — Dallas, Texas, United States (enrolling)
- University of Washington — Seattle, Washington, United States (enrolling)
- Centre Hospitalier Régional Universitaire de Montpellier - Hôpital Arnaud de Villeneuve — Montpellier, France (enrolling)
- Hôpital Necker Enfants Malades — Paris, France (enrolling)
- UMC Utrecht — Utrecht, Netherlands (enrolling)
- The University of Alabama at Birmingham — Birmingham, Alabama, United States (enrolling)
- University Hospitals Birmingham — Birmingham, United Kingdom (enrolling)
- Royal Papworth Hospital — Cambridge, United Kingdom (enrolling)
- Leeds Teaching Hospitals — Leeds, United Kingdom (enrolling)
- King's College Hospital — London, United Kingdom (enrolling)
- Nottingham University Hospitals — Nottingham, United Kingdom (enrolling)
- New Zealand Clinical Research (Part 1 Only) — Auckland, New Zealand
Full record on ClinicalTrials.gov
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