Cognitive Enhancement Through Model-based and Individualized Neurostimulation

Completed · Not applicable · Has a placebo group

Conditions studied: Transcranial Electrical Stimulation (tES)

In brief

The goal of this clinical trial is to learn about the effects of transcranial electric stimulation on attentional control and brain dynamics in healthy adults. The main questions are: Does stimulation affect how subjects exert attentional control? Do mathematical models predict brain activity changes in response to stimulation? Participants will have electroencephalography (EEG) brain data recorded while: They sit relaxed They receive stimulation, while relaxed They receive stimulation while completing computerized tasks to measure cognitive abilities ("cognitive tasks") They receive sham (ineffective) stimulation during cognitive tasks

Key facts

Study ID

NCT06235970

Run by

Washington University School of Medicine

People needed

17

Starts

2024-02-13

Expected to finish

2025-12-31

Last updated by the study team

2026-05-07

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy younger adults (ages 18 to 45). Community-living men, women or non-binary, aged 18-45

You may not qualify if…

• Taking psychotropic medication or medication with cognitive side effects
• Medical disorder that affects cognitive or motor function
• Past/present head injury associated with loss of consciousness or neurological sequelae
• Prior occurrence of seizure of any origin
• Skin conditions affecting the scalp
• Scalp tattoos
• Rashes, sores or open wounds on scalp or face

Where it is running

• Washington University — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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