Multimodal Musical Stimulation for Healthy Neurocognitive Aging
Recruiting now · Not applicable
Conditions studied: Aging
In brief
This is a Stage I randomized, sham-controlled trial on the effects of multimodal musical stimulation on working memory in aging. Neurologically healthy older and younger adults will be tested on working memory and electroencephalography in the first randomized controlled trial of music as a form of brain stimulation, with multimodal musical stimulation and control stimulation conditions. Results will test the causal role of oscillatory mechanisms of the brain on cognition, and will lay the groundwork to the first musical, neurophysiologically targeted, brain-stimulation device for reversing cognitive decline in aging.
Key facts
- Study ID
- NCT06229093
- Run by
- Northeastern University
- People needed
- 100
- Starts
- 2022-12-11
- Expected to finish
- 2027-12-31
- Last updated by the study team
- 2025-07-10
Who can join
Age: 18 and older, up to 95. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- normal or corrected-to-normal vision
- no more than mild hearing loss
- no recent history of neurological or psychiatric disorders, including mood disorders or use of medications that may affect cognition or responsiveness to music.
You may not qualify if…
- moderate or severe hearing loss (40+ dB)
- visual impairment (including color blindness) that cannot be corrected with glasses or contacts
- recently changed dosage of cholinesterase inhibitors or psychotropic medication
- recent history of psychotic or schizophrenic episodes
- major neurologic diagnosis or other condition that might impair cognition or confound assessments (dementia, ADRD; Parkinson's disease, stroke, brain injury, epilepsy, or recent cardiovascular or neurovascular event)
- recent history of serious physical trauma or diagnosis of serious chronic health condition requiring medical treatment and monitoring .
Where it is running
- Northeastern University — Boston, Massachusetts, United States (enrolling)
Full record on ClinicalTrials.gov
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