A Clinical Study to Map the HLA Genomic Region in the Greek Population

Recruiting now

Conditions studied: Healthy, Respiratory Disease, Chronic Renal Failure, Cardiovascular Diseases, Metabolic Disease, Psychiatric Disorder, Neurologic Disorder, Gastrointestinal Diseases, Haematologic Disease, Rheumatologic Disease

In brief

The aim of GENESIS clinical study is to map the HLA genomic region in the Greek population and evaluate possible correlations with selected underlying diseases.

Key facts

Study ID

NCT06227468

Run by

Athens LifeTech Park

People needed

12000

Starts

2023-12-12

Expected to finish

2026-08-31

Last updated by the study team

2024-01-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The study will include adult subjects (age ≥ 18) that:
• possess a Greek social security number and are visiting hospitals/clinics, and/or other private laboratory institutions (incl. clinics and health care groups) as part of standard clinical practice in Greece,
• are willing and able to provide written informed consent to participate in the study according to the study protocol.

You may not qualify if…

• Subjects not able to provide written informed consent (e.g. ICU patients, mental illness patients, lack of legal capacity).
• Subjects who have had an allogeneic (non-self-donor):
• bone marrow transplant
• stem cell transplant
• blood transfusion less than two weeks prior to buccal swab sample collection
• liver transplant
• Subjects who participated in an interventional clinical trial in the past that according to the subject's physician opinion might have had an impact on their HLA genome.

Where it is running

• Department of Infectious Diseases, 2nd Department of Internal Medicine, University General Hospital of Alexandroupolis — Alexandroupoli, Greece (enrolling)
• Department of Respiratory, University Hospital of Ioannina — Ioannina, Greece (enrolling)
• Department of Respiratory Medicine, University General Hospital of Alexandroupolis — Alexandroupoli, Thrace, Greece (enrolling)
• Department of Rheumatology, University Hospital of Heraklion — Heraklion, Greece
• 2nd Propaedeutic Department of Internal Medicine, Attikon University General Hospital — Chaïdári, Attica, Greece
• Department of Haematology, University General Hospital of Larissa — Larissa, Greece
• 2nd Department of Neurology, AHEPA University Hospital — Thessaloniki, Thessaloniki, Greece
• Department of Cardiology, University General Hospital of Heraklion — Heraklion, Greece

Full record on ClinicalTrials.gov

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