A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Recruiting now · Phase 2 · Has a placebo group
Conditions studied: Inflammatory Bowel Diseases, Crohn's Disease
In brief
This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 3 active dose regimens of MORF-057 in adult study participants with moderately to severely active Crohn's disease (CD).
Key facts
- Study ID
- NCT06226883
- Run by
- Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
- People needed
- 385
- Starts
- 2024-07-18
- Expected to finish
- 2030-06-01
- Last updated by the study team
- 2026-07-20
Who can join
Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Pesquisare — Santo André, Brazil (enrolling)
- Scarborough Center for Inflammatory Bowel Disease — Scarborough, Canada (enrolling)
- Salzburg Regional Hospital — Salzburg, Austria (enrolling)
- Chronos Pesquisa Clínica — Brasília, Brazil (enrolling)
- Clínica Hepatogastro JK — São Paulo, Brazil (enrolling)
- Diex Recherche Quebec Inc. — Québec, Canada (enrolling)
- Atlanta Gastroenterology Specialists, PC — Atlanta, Georgia, United States (enrolling)
- Medical University Hematology — Innsbruck, Austria (enrolling)
- University Hospital St. Poelten — Sankt Pölten, Austria (enrolling)
- Medical University of Vienna — Vienna, Austria (enrolling)
- Peak Gastroenterology Associates - Colorado Springs — Colorado Springs, Colorado, United States (enrolling)
- Cross Creek Medical Clinic — Fayetteville, North Carolina, United States (enrolling)
- Nova Scotia Health Authority — Halifax, Canada (enrolling)
- London Health Sciences Centre — London, Canada (enrolling)
- Palmetto Gastroenterology Clinical Research — Summerville, South Carolina, United States (enrolling)
- Gastrointestinal Associates of Northeast Tennessee — Johnson City, Tennessee, United States (enrolling)
- GI Alliance - Cedar Park — Cedar Park, Texas, United States (enrolling)
- Clinical Research of Osceola — Kissimmee, Florida, United States (enrolling)
- The University of Texas Health Science Center at Houston — Houston, Texas, United States (enrolling)
- Tandem Clinical Research — Houma, Louisiana, United States (enrolling)
- Gastro Care Institute — Lancaster, California, United States (enrolling)
- Tyler Research Institute, LLC — Tyler, Texas, United States (enrolling)
- Care Access Research - Ogden — Ogden, Utah, United States (enrolling)
- Gastroenterology Associates of Central Virginia — Lynchburg, Virginia, United States (enrolling)
- Mount Sinai Hospital — Toronto, Canada (enrolling)
Full record on ClinicalTrials.gov
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