Multi-omics Study for Early Detection of Colorectal Cancer (MOED-CRC)
Recruiting now
Conditions studied: Colorectal Cancer, Adenomatous Polyps, Adenoma, Advanced Adenoma
In brief
The primary objective of the study is to screen multi-omics markers in blood samples and construct a prediction model for CRC based on liquid biopsy, and we will further optimize the prediction model by validating its clinical performance externally.
Key facts
- Study ID
- NCT06220617
- Run by
- Zhejiang University
- People needed
- 3600
- Starts
- 2024-01-11
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2024-01-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- History of other malignant tumors (excluding non-melanoma skin cancer).
- Prior or related treatments previously (including colorectal cancer or advanced adenoma surgery, endoscopic treatment, chemotherapy, targeted therapy, immunotherapy, radiation, neoadjuvant therapy, etc.).
- Patients with hereditary colorectal diseases (including Lynch syndrome, familial CRC type X (FCCX), familial adenomatous polyposis (FAP), MUTHY-associated polyposis (MAP), Peutz-Jeghers syndrome (PJS), juvenile polyposis syndrome (JPS), serrated polyposis syndrome (SPS), etc.).
- Usage of anti-tumor drugs such as methotrexate, cyclophosphamide, mercaptopurine, and bendamustine for other diseases within 30 days before blood collection.
- Prior blood transfusion (including blood components) within the past 2 weeks.
- Prior organ transplantation, bone marrow transplantation, or stem cell transplantation.
- Pregnancy women.
- Prior or current anti-infection treatment within 14 days before blood collection.
- Inability to comply with study procedures such as blood collection and related examinations.
- Deemed unsuitable for participation in the clinical trial by the investigator.
Where it is running
- Henan Cancer Hospital Affiliated Cancer Hospital of Zhengzhou University — Zhengzhou, China (enrolling)
- The Second Affiliated Hospital of Zhejiang University — Hangzhou, Zhejiang, China (enrolling)
- Sun Yat-Sen University Cancer Hospital — Guangzhou, China (enrolling)
- Yunnan cancer hospital — Kunming, China (enrolling)
- Jiangsu province hospital — Nanjing, China (enrolling)
- The first affiliated hospital of Xi'an Jiaotong University — Xi'an, China (enrolling)
Full record on ClinicalTrials.gov
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