The Safe Fast Track Study

Recruiting now · Not applicable

Conditions studied: Emergency Department, Non-specific Complaints

In brief

Emergency departments (ED) internationally are treating an increasing number of patients. Most require hospital services but some could be better cared for on alternative pathways. D-dimer has some unique properties. It is non-specific and is elevated in many acute condi- tions; but conversely remains normal in the absence of significant disease. Previous studies have shown that having a normal D-dimer on arrival to the emergency department is associated with a very low risk of 30-day all-cause mortality. The investigators propose a multicenter randomized controlled trial using D-dimer to identify patients at low risk and test if providing this information will change time to discharge disposition by the treating physician.

Key facts

Study ID

NCT06219486

Run by

Odense University Hospital

People needed

1538

Starts

2024-01-22

Expected to finish

2025-08-01

Last updated by the study team

2025-04-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 or above
• Able to provide oral and written informed consent in Danish
• Blood tests ordered on arrival as part of standard of care
• Ambulatory on arrival or walking to the ambulance (i.e., stable independent gait)
• Normal vital signs (i.e., National Early Warning Score \< 3)

You may not qualify if…

• Unstable condition requiring immediate care in the resuscitation area
• Triage level red (i.e., the most urgent patients)
• Trauma (minor and major) patients
• High likelihood of requiring a D-dimer analysis on clinical indications during the current hospital contact (e.g., suspected venous thromboembolic disease) that will be ordered on arrival regardless of this study
• Previous participation in the study

Where it is running

• Esbjerg Hospital — Esbjerg, Syd, Denmark (enrolling)
• Odense University Hospital — Odense, Syd, Denmark

Full record on ClinicalTrials.gov

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