A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation

Recruiting now · Not applicable

Conditions studied: Transfemoral Amputation, Limb Loss, Limb Absence

In brief

Microprocessor-controlled knees (MPKs) do not typically utilize motors to power joint rotation, but they automatically adjust resistance or damping in the joint to improve swing- and/or stance-phase control as appropriate for the prosthesis user during gait. The Ossur Power Knee is the only commercially-available MPK that uses a motor to provide active power generation during walking and other activities. The purpose of this proposed investigation is to perform and compare biomechanical evaluations of the Power Knee and Ossur Rheo XC, a passive MPK, during walking and other activities by prosthesis users. Furthermore, mobility between male and female subjects will be compared to determine if there are differences in prosthetic knee usage on the basis of sex.

Key facts

Study ID

NCT06218238

Run by

VA Office of Research and Development

People needed

20

Starts

2024-04-01

Expected to finish

2027-03-31

Last updated by the study team

2025-09-09

Who can join

Age: 45 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Unilateral, transfemoral amputation (any etiology).
• Age from 45-75 years.
• Residual limb length classified as standard (i.e., medium) to long.
• Prosthesis user for at least 1 year prior to enrolling in the study.
• K3 or K4 level ambulator.
• Good sensation on their residual limb(s) (upon routine clinical examination).
• Good skin integrity upon visual inspection.
• Does not require the use of assistive devices to walk for short distances.
• Not currently taking medications that are known to affect balance or gait.
• Presents with good socket fit based upon a standard assessment by the study prosthetist.

You may not qualify if…

• Bilateral amputations
• Individuals with a knee disarticulation

Where it is running

• Jesse Brown VA Medical Center, Chicago, IL — Chicago, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

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