Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation

Recruiting now · Not applicable

Conditions studied: COPD

In brief

In our study, changes in vastus lateralis muscle oxygenation will be evaluated with the Moxy device, a functional infrared oxygen measurement device, during the inspiratory muscle fatigue protocol in COPD cases and the healthy control group.

Key facts

Study ID: NCT06217276
Run by: Istanbul Medipol University Hospital
People needed: 30
Starts: 2024-01-20
Expected to finish: 2026-01-15
Last updated by the study team: 2025-05-01

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Having a diagnosis of Stage 2-3 COPD according to the following clinical diagnostic criteria according to the American Thoracic and European Respiratory Societies (ATS-ERS).
Having been using the same medications for the last 4 weeks

You may not qualify if…

Patients with severe comorbid diseases, unstable coronary artery disease, collagen vascular diseases and requiring high-flow oxygen therapy (˃ 3-4 L\\min).
Presence of any vascular problem that may affect lower extremity muscle oxygenation
Presence of another respiratory system disease other than COPD
Patients who have had an acute COPD exacerbation in the last 4 weeks
Patients experiencing COPD exacerbations during the study protocol
Presence of fatty tissue or scar tissue at the measurement points, which may impair the measurement quality.
Have already participated in another clinical trial within the last 30 days that may affect the results of the study.
Inclusion Criteria for Healthy Cases
Being over 18 years of age
Not having any diagnosed chronic disease
Not being a smoker

Where it is running

Yedikule Chest Disease Hospital — Istanbul, Zeytinburnu, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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