Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients

Recruiting now · Not applicable

Conditions studied: Lung Cancer

In brief

The goal of this clinical trail is to compare the effects of preoperative exercise training of different intensities on short-term cardiorespiratory function and postoperative outcomes in patients scheduled for lung resections.

Key facts

Study ID

NCT06215326

Run by

Guangdong Provincial People's Hospital

People needed

100

Starts

2024-01-23

Expected to finish

2027-07-31

Last updated by the study team

2026-08-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age>18 years.
• Suspected or confirmed primary lung cancer with scheduled surgical treatment.
• Moderate-to-high perioperative risk, defined as FEV1<60% of predicted value (wedge) or ppo FEV1<60% of predicted value (lobectomy/segmentectomy) or VO2peak<20 ml/kg/ min.
• Sign informed consent and accept to comply with the requirements of the study protocol.
• Completion of a baseline Complete cardiopulmonary exercise testing (CPET).

You may not qualify if…

• Concurrent or previous history of other malignant tumors.
• Life expectancy less than 1 year.
• Dementia; infirmity; or inability to participate in sports (musculoskeletal limitations, namely, injuries, frailty, and weakness).
• Inability to maintain exercise training.
• Irregular vital signs (heart rate: < 40 or > 120 bpm at rest; blood pressure: systolic blood pressure > 200 mm Hg or diastolic pressure > 110 mm Hg; T: ≥ 38.5 or ≤ 36◦C; SpO2 ≤ 90%).
• Currently enrolling in any other clinical trials.
• Patient refusal.

Where it is running

• Guangdong Provincial People's Hospital — Guangzhou, Guangdong, China (enrolling)

Full record on ClinicalTrials.gov

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