Cognitive Leisure and Preclinical Alzheimer's Disease: Exploring Neural Mechanisms

Recruiting now

Conditions studied: Cognitive Dysfunction

In brief

The goal of this clinical trial is aims to: 1. Translate and culturally adapt the Cognitive Leisure Activity Scale (CLAS) into Chinese and Conduct reliability and validity tests for the Chinese version of CLAS. 2. Investigate the correlation between cognitive leisure activity levels and cognitive function in the preclinical stage of Alzheimer's Disease (AD). 3. Clarify the regulatory mechanisms of cognitive leisure activity levels on the neural circuits of patients in the preclinical stage of AD.

Key facts

Study ID

NCT06215274

Run by

Yuanjiao Yan

People needed

156

Starts

2024-04-27

Expected to finish

2026-12-31

Last updated by the study team

2024-05-17

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Clinical diagnosis of Mild Cognitive Impairment (MCI) and Subjective Cognitive Decline (SCD)
• Age ≥ 60 years
• Capable of normal communication in Mandarin，possesses a certain level of comprehension and judgment.

You may not qualify if…

• Individuals with severe hearing or language impairments, or with severe physical illnesses that are unable to cooperate with the survey
• Individuals with pacemakers, metallic implants, cochlear implants, claustrophobia, and other contraindications for MRI examination.

Where it is running

• Fujian Provincial Hospital — Fuzhou, Fujian, China (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.