Speculum Insertion During Embryo Transfer

Recruiting now · Not applicable

Conditions studied: IVF

In brief

Lubrication gels are widely used in numerous gynecologic procedures in order to ease the insertion of speculum and visualize the cervix. It was shown that applying lubricating gels significantly decreases patient pain during vaginal speculum examination. While many fertility specialists use lubrication gels to insert the speculum during embryo transfer (ET), others are strongly reluctant to use gels due to concern that they might have a detrimental effect on embryos and ET success. Similar concern was prevalent regarding the use of lubrication gel during Pap-smear for detection of cervical dysplasia. However, several studies have shown that the use of small amount of water-soluble gel does not change cervical cytology. Lubrication gels might have deleterious effect on sperm motility. However, there wasn't any study examining the effect of lubricant gel on ET success. The investigators hypothesize that using a lubrication gel will not reduce the live birth rate per transfer, but decrease patient pain during procedure.

Key facts

Study ID

NCT06210451

Run by

Wolfson Medical Center

People needed

416

Starts

2024-05-01

Expected to finish

2026-12-31

Last updated by the study team

2024-07-24

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Age 18-40
• Fresh and thawed ET
• Patients undergoing their 1st-3rd ET
• ET of 1-2 embryos

You may not qualify if…

• Age>40
• Egg donation cycles

Where it is running

• Faculty of Medical and Health Sciences — Tel Aviv, Israel (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.