Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study

Running, not enrolling · Not applicable

Conditions studied: Abuse Tobacco, Exposure

In brief

This study evaluates how synthetic cooling additives like WS-3 and WS-23 impact e-cigarette perceptions, use behavior, and toxicant exposure.

Key facts

Study ID

NCT06208202

Run by

Ohio State University Comprehensive Cancer Center

People needed

158

Starts

2024-05-08

Expected to finish

2028-06-01

Last updated by the study team

2026-06-15

Who can join

Age: 21 and older, up to 29. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged 21-29 years
• Current e-cigarette (EC) user (defined as ≥ weekly use over the past 3 months)
• Willing to provide informed consent and abstain from using their EC at least 12 hours prior to the four lab sessions
• Read and speak English

You may not qualify if…

• Recently COVID-19+ (defined as positive test in the past 30 days) or a recent COVID-19 hospitalization (defined as a hospitalization within the past 6 months)
• Unstable or significant psychiatric conditions (past and stable conditions will be allowed)
• History of cardiac event or distress within the past 3 months
• Are currently pregnant, planning to become pregnant, or breastfeeding (will be verified with urine pregnancy test)
• Have suffered from any serious lung disease or infection (e.g. , tuberculosis, cystic fibrosis, or lung cancer) in the past 30 days
• Have hemophilia or another type of bleeding disorder
• Are blind, severely visually impaired, deaf, hard of hearing, or have a severe motor disability

Where it is running

• Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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