A EUropean REgistry and Sample Sharing networK to Promote the Diagnosis and Management of Light Chain Amyloidosis (EUREKA)

Recruiting now

Conditions studied: AL Amyloidosis

In brief

A prospective patients' registry collecting all new cases of AL amyloidosis evaluated at referral Centers from across Europe and a sample sharing network will be created to study mechanisms of the disease through the use of advanced molecular technologies and big data analysis tools.

Key facts

Study ID

NCT06205953

Run by

Fondazione IRCCS Policlinico San Matteo di Pavia

People needed

400

Starts

2024-01-01

Expected to finish

2026-06-01

Last updated by the study team

2026-04-16

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• diagnosis of systemic AL amyloidosis;
• treatment-naïve;
• age ≥18 years;
• ability to understand and willingness to sign an informed consent;
• planned follow-up at participating center.

You may not qualify if…

• non-AL amyloidosis;
• previous treatment for AL amyloidosis.

Where it is running

• Medical Department, Amyloidosis Center, University Hospital, Im Neuenheimer Feld 672 — Heidelberg, Germany (enrolling)
• Fondazione IRCCS Policlinico San Matteo, Pavia, Viale Golgi 19, 27100 — Pavia, Italy (enrolling)
• UMC Utrecht, dept Hematology, Amyloid Expertise Center, Utrecht, Heidelberglaan — Utrecht, Netherlands (enrolling)
• Instituto de Investigación Sanitaria de Navarra (IdiSNA) C. de Irunlarrea, 3, 31008 Pamplona, Navarra — Pamplona, Spain (enrolling)
• Universidad de la Republica Hospital de Clinicas "Dr Manuel Quintela" — Montevideo, Uruguay (enrolling)
• University of Applied Sciences and Arts Northwestern Switzerland, Institute of Medical Engineering and Medical Informatics — Muttenz, Switzerland

Full record on ClinicalTrials.gov

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