High Versus Low Dose Serratus Anterior Plane Block After Minimally Invasive Valve Surgery.
Recruiting now · Not applicable
Conditions studied: Analgesia, Surgery, Cardiac Disease, Post Operative Pain
In brief
This study aims to compare the efficacy and quality of pain relief provided by the high-dose serratus anterior plane (SAP) block with the standard SAP block in preventing and treating acute postoperative pain after total endoscopic aortic or mitral valve surgery.
Key facts
- Study ID
- NCT06205875
- Run by
- Jessa Hospital
- People needed
- 100
- Starts
- 2024-02-21
- Expected to finish
- 2027-12-31
- Last updated by the study team
- 2025-05-14
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Scheduled for elective aortic valve surgery or elective mitral valve surgery via right anterolateral thoracotomy
- Adult patients (minimally 18 years old)
- Bodyweight > 50kg
- EuroScore ii < 3%
You may not qualify if…
- Refusal to participate
- Inability to communicate due to language or neurologic barriers
- Inability to control and self-administer opioids with PCIA or to comprehend the NRS pain score due to confusion or learning difficulties
- Chronic use of opioids
- Chronic use of analgesic antidepressants and/or antiepileptics
- Use of prohibited medication which possibly interacts with bupivacaine-epinephrine or opioids (mexiletine, ketoconazole, theophylline, IMAO, Digitalis and cimetidine)
- History of major trauma or surgery to right chest wall
- History of chronic pain at right chest wall
- Allergy to opioids and/or local anesthetics
- Allergy to paracetamol
- Class 3 obesity (BMI 40 or more)
- Pregnancy
- Intraoperative events compromising early postoperative recovery (aortic dissection, systolic anterior motion of the mitral valve, cardiac tamponade, brady-arrhytmias requiring external pacing,...)
Where it is running
- Jessa hospital — Hasselt, Limburg, Belgium (enrolling)
Full record on ClinicalTrials.gov
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